This report 44 presents the results of SARS-CoV-2 contamination of wastewater at the entrance of 13 wastewater treatment plants (WWTPs) at the beginning of the fourth week of 2021. As the previous week, the SARS-CoV-2 RNA fluxes in sewage treatment plants were still important at the beginning of the week 04, but with a decreasing trend, indicating a medium prevalence of the virus in sewage at national and regional level. The downward trend corresponds to an average reduction of about 1.2 log compared to the maximum peak of the current wave. At the level of the treatment plant, similar dynamic patterns were observed, with a decreasing trend for all the plants analysed. For some of them, RT-qPCR signal is approaching to the limit of quantification of our assays.
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